Pure Yohimbine Hydrochloride 98% (CAS: 65-19-0)
Product Name: Yohimbine hydrochloride
Synonyms: CORYNINE HYDROCHLORIDE; APHRODINE HYDROCHLORIDE; APHROSOL HYDROCHLORIDE; 17-HYDROXYYOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE; YOHIMBE HCl; YOHIMBINE HCl; YOHIMBINE HYDROCHLORIDE; Yohimbe Bark P. E; Plant extracts
Apperance: White to slightly yellow powder
Usage: Indole alkaloid with α 2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.
Patients sensitive to rauwolfia alkaloids such as deserpidine, rauwolfia serpentina, or reserpine may also be sensitive to yohimbine.
Yohimbine readily penetrates the (CNS) and produces a complex pattern of responses in lower doses than those required to produce peripheral alpha-adrenergic blockade. These include, anti-diuresis, a general picture of central excitation including elevation of blood pressure and heart rate, increased motor activity, nervousness, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. Also, dizziness, headache skin flushing reported when used orally.
Generally, this drug is not proposed for use in females and certainly must not be used during pregnancy. Neither is this drug proposed for use in pediatric, geriatric or cardio-renal patients with gastric or duodenal ulcer history. Nor should it be used in conjunction with mood- modifying drugs such as antidepressants, or in psychiatric patients in general.
Renal diseases and patient's sensitive to the drug. In view of the limited and inadequate information at hand, no precise tabulation can be offered of additional contraindications.