lidocaine
group nameLocal Anesthetic
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Min Order10 gram
brand nameJNJG
model137-58-6
payment method
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update timeWed, 15 Mar 2017 11:32:35 GMT
Paramtents
CAS NO 137-58-6
MF C14H22N2O
MW 234.34
Purity 99%
Appearance White crystalline powder
Certification GMP, ISO 9001, USP, BP
Standard pharma grade
Usage can be used as pharmaceutical material
Packging & Delivery
Min Order10 gram
Briefing
Detailed
lidocaine /Xylocaine
EMAIL: cgf at chembj dot com
Skype: cgf..........com
Whatsapp: +8615564141272
Synonyms: 2-(Diethylamino)-2',6'-acetoxylidide;2-(diethylamino)-2,6'-acetoxylidide;2-(diethylamino)-n-(2,6-dimethylphenyl)-acetamid;2',6'-Acetoxylidide, 2-(diethylamino)-;6'-acetoxylidide,2-(diethylamino)-2;Acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-;Acetamide,2-(diethylamino)-N-(2,6-dimethylphenyl)-;a-Diethylamino-2,6-acetoxylidide
MF: C14H22N2O
MW: 234.34
EINECS: 205-302-8
Melting point: 66-69°C
storage temp: Store at RT
solubility ethanol: 4 mg/mL
form: powder
Water Solubility: practically insoluble
Stability: Stable. Incompatible with strong oxidizing agents.
Certification: GMP, ISO 9001, USP, BP
Standard: pharma grade
Description:
Lidocaine is a local anesthetic, also known as Xylocaine, in recent years it has been replaced procaine, widely used in local infiltration anesthesia in cosmetic plastic surgery, it can block the nerve excitability and conduction by inhibiting the sodium channels of nerve cell membrane. The fat soluble and protein binding rate of lidocaine is higher than procaine, its cell penetrating ability is strong, fast onset, long duration of action, the interaction strength is 4 times of procaine.
Lidocaine is used in infiltration anesthesia, epidural anesthesia, topical anesthesia (including thoracoscopy or abdominal surgery for mucosal anesthesia) and nerve block. In order to extend the time of anesthesia, reduce the poisoning of lidocaine and other side effects, can be added in the anesthetic epinephrine.
Lidocaine can also be used for the treatment of ventricular premature beat after acute myocardial infarction, ventricular tachycardia, digitalis poisoning, cardiac surgery and cardiac catheterization-induced ventricular arrhythmias, including ventricular premature beats, ventricular tachycardia and ventricular fibrillation. Lidocaine is also used for duration status of epilepsy which other anti-seizure drugs are not effective, as well as local or spinal anesthesia. But it is usually ineffective for supraventricular arrhythmias.
Applications:
Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds. Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiace.
Chemical property:
Lidocaine is white needle like crystals, and its melting point is 68-69℃; boiling point is 180-182℃ (0.53kPa), soluble in ethanol in 159-160℃ (0.267kPa), ether, benzene, chloroform and oil, do not dissolve in water. In common use radical hydrochloride, lidocaine hydrochloride (C14H22N2O • HCL, [73-78-9]) is a white crystalline powder. Melting point 127-129℃, and the monohydrate melting point is 77-78℃. Easily soluble in water, 0.5% aqueous solution pHO 4.0-5.5. Odorless, bitter taste.
Uses:
This product is a local anesthetics of amide derivatives，and widely used in surface anesthesia, anesthesia, conduction anesthesia and epidural anesthesia. The LD50 of oral lidocaine hydrochloride to mice was 290 mg/kg.
Used as a local anesthetic.
Usage Lidocaine (Alphacaine)is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Histamine is responsible for many features of allergic reactions. Lidocaine (Alphacaine)is a second-generation antihistamine agent closely st
Usage antihypertensive
Usage Anticonvulsant
Usage Antiarrhythmic Agents, Anesthetics
Packing:
Discreet packing ways as your requirement, 100% go through.
Storage:
Store in cool and dry area and keep away from direct sunlight.
Advantage:
1. We have experience in exporting Pharma Chemicals, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation!
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