Adipotide

  • group namePolypeptides

  • Min Order1 milligram

  • brand nameJNJG

  • model121062-08-6

  • payment method

  • update timeWed, 15 Mar 2017 14:46:49 GMT

Paramtents

  • CAS NO 121062-08-6

  • MF 78H111N21O19

  • MW 255.22

  • Purity 99%

  • Appearance White Lyophilized Powder

  • Certification GBP, ISO9001, FDA

  • Standard Enterprise standard

  • Usage The King of Weight Loss

Packging & Delivery

  • Min Order1 milligram

Briefing

Adipotide is an experimental treatment that prevents the blood supply to fat cells

Detailed

Adipotide


EMAIL: cgf at chembj dot com
Skype: cgf..........com
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CAS NO: 121062-08-6

MF: 78H111N21O19

MW: 255.22

Purity: 99%

Appearance: White crystalline powder.

Customized: on-Customized

Suitable: Adult

Certification: GMP, USP, USP

Standard: Enterprise standard

Usage: The King of Weight Loss



Description:


Aditpotide is an experimental weight loss peptidomimetic with the amino acid sequence CKGGRAKDC-GG-D(KLAKLAK)2, which has been developed by researchers in the United States in an effort to fight obesity. Peptidomimetics are small protein-like chains designed to mimic a peptide. The peptide called Adipotide has been developed by U.S. researchers in the fight against the obesity . This experimental treatment has reduced by 11% the weight of the treated monkeys by reducing fatty tissue, the BMI, and waist circumference.

Clinical Research studies have shown that the peptide-like compound, Adipotide, is able to kill fat cells thereby causing a decrease in the volume and mass of the subcutaneous fat, and this in turn leads to weight loss. Adipotide is able to kill the adipocytes (fat cells) by selectively causing programmed cell death (apoptosis) of the blood vessels supplying the adipocytes. Due to the deprivation of nutrient supply, the subsequent starvation (which causes cellular atrophy or decrease in cell size) and the accumulation of waste products in the adipocytes; an irreversible injury occurs and this leads the mitochondria to release protease enzymes called caspases (specific factors that initiate the apoptotic process) which activate the transcription (a process whereby DNA is used to create mRNA) and translation (a process whereby mRNA is used to create the nascent primary peptide) of gene sequences which ultimately leads to the production of proteins that effect the apoptotic process.

Molecular studies have revealed that Adipotide possess a unique stereo-chemical (3D) conformation which enables it to bind to only two receptors in the body: ANXA-2 and prohibitin. These receptors are located on the surface of the endothelium (innermost wall lining) of the blood vessels supplying the white adipocytes, and as such, these receptors confer tissue specificity to adipotide. Formation of white adipocytes only occurs when the extent of energy consumption far exceeds energy utilization, and its (white adipocytes) formation and accumulation in the subcutaneous layer serves as a hallmark of obesity.

Application:


Pathological studies have shown that obesity serves a risk factor for a myriad of diseases such as cancer, hypertension, endocrine disorders (such as diabetes mellitus, hyperlipidemias and metabolic syndrome), cardiovascular disease (such as stroke and myocardial infarctions) and degenerative diseases (such as osteoarthritis). Moreover, aberrant accumulation of white adipocytes predisposes the affected individual to lipoma and lipomatosis. It is well known that abdominal adiposity is mainly caused by white adipocytes, and this form of adiposity is the most lipolytically active, thus requiring a steady blood supply. Any interference with the blood supply causes it to activate the apoptotic process.

Adipotide is an experimental treatment that prevents the blood supply to fat cells. This has helped obese monkeys to lose on average 11% of their body weight in four weeks, perhaps opening the way for therapy in humans, according to a recent research study. The study, published in the journal Science Translational Medicine , shows that body mass index and waist circumference of the rhesus monkeys were reduced.

The experimental weight loss agent, "Adipotide" used by researchers at Anderson Center consists of a substance that binds to a protein on the surface of blood vessels nourishing fat cells as well as a synthetic peptide, destroying fat cells, say the authors of the study. These cells are then metabolized by the body that destroys them and excreted. An imaging test also showed a significant reduction in fatty tissue in the bodies of these animals compared to the untreated control group, the researchers suggest the Anderson Center for Research on Cancer , University of Texas (South). " The obesity as well as smoking is a major risk factor for cancer , "says Dr. Wadih Arap, professor of medicine at the Koch Center part of the University of Texas, a major sponsor of this research.


Packing:


Discreet packing ways as your requirement, 100% go through.

Storage:


Store in cool and dry area and keep away from direct sunlight.

Advantage:


1. Quality assurance
With our years of experience, advanced technology and continuous research, our quality is to fully meet the needs of the market to meet the requirements of customers, many customers use our products, we believe that the product is very good. Whether it is a powder, or liquid, yes, we all know, our liquid better.

2. Safe transportation
Our mode of transport is taken according to each country's situation is different transportation, while our packaging, according to the latest customs situation, constantly updated, improved our packaging, we guarantee that you receive it within 3-5 to your product.

3. The product diversity
Our products are powders and liquids, yes, brothers, the effect of the liquid is very good, but many people do not use liquid, so you are very lucky, you buy our powder, we can tell you the method of making the liquid If you buy a liquid, we will tell you how to filter. We absolutely guarantee that you can very safely use our products

4. High quality service
Our goods packing will not contain any hormone information and can be sent out from different areas of china. At present,the goods customs clearance rate we send to United states and Europe is 99%, As for Canada, Brazil of quite high buckle close rate area, we also have a new way to get through the customs. We also have completely re-send policy to some areas.

6YRS Jinan Jiage Biological Technology Co,Ltd

Nearest port for product export
shenzhen, shanghai
Delivery clauses under the trade mode
FOB
Acceptable payment methods
T/T, L/C, D/P D/A, MoneyGram, Credit Card, PayPal, Westem Union, Cash, Escrow
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