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Sermorelin is a grow hormone releasing hormone analogue.
Sermorelin is a grow hormone releasing hormone analogue. It is a 29-amino acid polypeptide representing the 1-29 fragment from endogenous human grow hormone releasing hormone, and is thought to be the shortest fully functional fragment of GHRH. It is used as a test for grow hormone secretion. It is also used as doping substance in sports. Used extensively in Anti-aging Therapy often in conjunction with Testosterone in men. Safer alternative to Human Grow Hormone
Useful for:Sermorelin is used in the treatment of prevention of HIV-induced weight loss, children with grow hormone deficiency or grow failure. Sermorelin should be considered a valuable alternative to HGH by anti-aging practitioners seeking to provide the best and most contemporary interventions in aging for their patients.
What is Oxytocin?
Oxytocin is a human peptide hormone and neuropeptide that is used as a medication to facilitate childbirth.Oxytocin is normally produced by the paraventricular nucleus of the hypothalamus and released by the posterior pituitary.It plays a role in social bonding, sexual reproduction in both sexes, and during and after childbirth.Oxytocin is released into the bloodstream as a hormone in response to stretching of the cervix and uterus during labor and with stimulation of the nipples from breastfeeding.This helps with birth, bonding with the baby, and milk production. Oxytocin was discovered by Henry Dale in 1906.Its molecular structure was discovered in 1952.
For Female, oxytocin is responsible for signaling contractions of the womb during labor. The hormone stimulates the uterine muscles to contract, so labor begins. It also increases the production of prostaglandins, which move labor along and increases the contractions even more.
Because of this effect, synthetic oxytocin is sometimes used to induce a woman to start labor if she cannot start naturally, or it can be given to make contractions stronger if a woman's labor is slowing.
Once the baby is born, oxytocin promotes lactation by moving the milk into the breast. When the baby sucks at the mother's breast, oxytocin secretion causes the milk to release so the baby can feed. At the same time, oxytocin is released into the brain to stimulate further oxytocin production. Once the baby stops feeding, the production of the hormone stops until the next feeding.
For Male, oxytocin function is less important, but it does have a role to play in moving sperm. It also appears to affect the production of testosterone in the testes.
A recent oxytocin study found that it is an important chemical messenger that controls some human behaviors and social interaction. It is oxytocin that triggers the bond between a mother and an infant, and it may also play a role in recognition, sexual arousal, trust and anxiety. Some research shows that the hormone may affect addiction and stress as well.
High and low oxytocin levels are possible, but research has not yet found any implications of these conditions. Men with high levels of oxytocin sometimes develop benign prostatic hyperplasia, or the enlarging of the prostate gland. This condition can cause urinary complaints. A lack of sufficient oxytocin can prevent the milk letdown reflex and make breastfeeding difficult. Also, some people with autism or who have autism spectrum disorders have low oxytocin levels. Low oxytocin levels have also been linked to depression and depression disorders, but using oxytocin to treat these conditions has not yet been studied sufficiently.
Oxytocin Dosage and usage:
Adult DoseInitial dose: 0.5 to 1 milliunits IV infusion per hour. At 30 to 60 minute intervals the dose should be gradually increased in increments of 1 to 2 milliunits until the desired contraction pattern has been established.
Usual Adult Dose for Postpartum Bleeding:
10 to 40 units IV infusion in 1000 mL at a rate sufficient to control bleeding.
10 units IM after delivery of placenta.
After suction or sharp curettage for an incomplete, inevitable or elective abortion:
10 units in 500 mL IV infusion. Adjust rate to assist uterus in contraction.
After intra-amniotic injection for midtrimester elective abortion:
10 to 20 milliunits per minute IV infusion. The total dose should not exceed 30 units in a 12 hour period due to the risk of water intoxication.
A study conducted to determine whether the freezing of oxytocin ampules adversely affects the oxytocin content found that oxytocin ampules could be safely used even if they have been temporarily frozen during transportation or storage.
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