Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic CAS:62-44-2

Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic CAS:62-44-2

  • group namePharmaceutical Raw Materials

  • Min Order1 piece

  • brand namekafen

  • model62-44-2

  • payment methodWestern Union, MoneyGram, T/T, Bitcoin

  • update timeWed, 14 Jun 2017 18:31:49 GMT

Paramtents

  • Melting point 133-138 ℃

  • Boiling point 355.1 ° C at 760 mmHg

Packging & Delivery

  • Min Order1 piece

Briefing

Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157

Detailed

Descriptions:
 
Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin.
 

3 Applications:
 
Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).
 
It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.
 
Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

Send Inquery

Email
Mobile
Content

I agree to the rules that follow the message

Trade Alert-Delivering the lastest product trends and industry news straight to your inbox